Expert Digestive Care in Greater Houston

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Accepting new patients at Cypress & Katy. Most insurance accepted.

Our Offices

Cypress · 21216 Northwest Freeway, Suite 640

Katy · Also accepting new patients →

Cypress Gastroenterology at a Glance

Digestive & Liver Specialist for Cypress, Northwest Houston, and Katy

Dr. Muhammad Ali Khan is a board-certified gastroenterologist with 18 years of clinical experience, serving patients in Cypress and Katy, TX. He provides comprehensive care for digestive and liver conditions, with expertise in colonoscopy, endoscopy, and colorectal cancer screening. Our Cypress clinic is located on Northwest Freeway (US-290).

Dr. Khan’s expertise encompasses the evaluation and management of acid reflux and GERD, irritable bowel syndrome (IBS), Crohn’s disease, ulcerative colitis, abdominal pain, rectal bleeding, and fatty liver disease. His approach emphasizes careful evaluation, clear communication, and personalized treatment plans tailored to each patient’s symptoms, medical history, and digestive health needs.

Medically reviewed by Muhammad Ali Khan, MD · Updated October 2026

GI & Liver SpecialistGastroenterology, hepatology & internal medicine
Memorial Hermann CypressHospital affiliation
Former MD Anderson FacultyAssociate Professor, UT MD Anderson
100+ Published ArticlesPeer-reviewed gastroenterology research

Symptom Guide

What Digestive Symptoms Are You Experiencing?

Symptoms that keep coming back, get worse or disrupt daily life deserve a medical evaluation. Choose a symptom to see common causes and how Dr. Khan evaluates it. These pages explain possible causes; they cannot diagnose your symptoms.

Cypress GI Services

Gastroenterology Services in Cypress

A gastroenterologist, also called a digestive disease specialist, treats the esophagus, stomach, intestines, colon, pancreas, gallbladder and liver. At the Cypress office, Dr. Khan evaluates new symptoms, manages long-term conditions and performs diagnostic and screening procedures.

Colonoscopy in Cypress

Screening for colorectal cancer from age 45, polyp removal and evaluation of rectal bleeding or bowel changes, with sedation for comfort.

Upper Endoscopy (EGD)

A direct look at the esophagus, stomach and duodenum to evaluate reflux, trouble swallowing, ulcers, bleeding or H. pylori, with biopsies when needed.

IBS Care

Recurring abdominal pain with diarrhea, constipation or both. Dr. Khan rules out celiac disease and IBD first, then builds a diet and medication plan.

Acid Reflux & GERD

Heartburn more than twice a week or reflux that continues on medication, evaluated with EGD when swallowing trouble or weight loss is present.

Crohn’s & Ulcerative Colitis

Diagnosis and long-term management of inflammatory bowel disease, including flare control, monitoring and treatment adjustments.

Liver Care (Hepatology)

Evaluation of fatty liver disease, abnormal liver enzymes and other liver conditions, including FibroScan liver stiffness testing.

All Treatments & Procedures →

COLORECTAL CANCER SCREENING

Is It Time to Discuss Colorectal Cancer Screening?

The U.S. Preventive Services Task Force recommends colorectal cancer screening for adults ages 45 to 75 who are at average risk. People with a family history of colorectal cancer or advanced polyps, inflammatory bowel disease or certain inherited syndromes may need to start earlier or be screened more often. Symptoms such as rectal bleeding call for a diagnostic evaluation rather than routine screening.

Learn About Screening Options
Dr. Muhammad Ali Khan, MD, board-certified gastroenterologist and hepatologist

MEET YOUR CYPRESS GASTROENTEROLOGIST

Meet Muhammad Ali Khan, MD, FACP, FASGE

Gastroenterologist & Hepatologist

Dr. Muhammad Ali Khan is a board-certified gastroenterologist providing comprehensive digestive care to the Cypress community at United Gastroenterology Associates on the Northwest Freeway (US-290). A Fellow of the American College of Physicians (FACP) and the American Society for Gastrointestinal Endoscopy (FASGE), he trained at Dow Medical College, the University of Toledo and the University of Tennessee Health Science Center, and served as an Associate Professor at The University of Texas MD Anderson Cancer Center. He has authored more than 100 peer-reviewed articles in gastroenterology and hepatology. His practice focuses on diagnostic and therapeutic endoscopy, colorectal cancer prevention, inflammatory bowel disease and liver disease, with each plan built around the patient’s history and goals. Read Dr. Khan’s full profile

Schedule with Dr. Khan →

PATIENT TESTIMONIALS

What Our Patients Are Saying

★★★★★
5.0-star rated digestive disease specialist with 270+ Google patient reviews
Cypress office · Read Cypress reviews →

“

Dr. Khan is an amazing physician. He is so kind hearted & wants to help you in every way possible. He listens & doesn’t make you feel rushed.

Donna L.

Cypress

“

Great staff and doctor! Very thorough and explained everything from the prep, procedure, and follow-up. I highly recommend Dr. Khan!

Huong V.

Cypress

“

Dr Khan is fantastic and has really good bed side manner. He took his time to listen to my concerns and address them accordingly. I will definitely be referring everyone I know to him!

Theresa M.

Cypress

Office Location

Visit Our Cypress Gastroenterology Office

Consultations, procedure planning and follow-up visits for digestive and liver concerns. If a procedure is recommended, the scheduling team confirms where it will take place.

Cypress Office

Address: 21216 Northwest Freeway, Suite 640
Cypress, TX 77429

Location: On the Northwest Freeway (US-290)

Hours: Monday–Friday, 8:30 a.m.–5:00 p.m.
Closed 12:00–1:30 p.m. for lunch

Phone: (346) 340-4414

Serving: Cypress, Towne Lake, Bridgeland, Fairfield, Copperfield and Jersey Village

Insurance & New Patient Information

United Gastroenterology Associates is accepting new patients and accepts most major insurance plans, including the carriers shown here. The office verifies your benefits before your visit, and self-pay options are available. For your first appointment, bring a photo ID, your insurance card, a list of your medications, any referral your plan requires and recent lab, imaging or procedure reports.

A carrier logo does not guarantee coverage for a specific plan or service. Call (346) 340-4414 to confirm your benefits.

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Frequently Asked Questions

What does a gastroenterologist do?

A gastroenterologist is a doctor who specializes in the digestive system and liver. Gastroenterologists diagnose and treat conditions such as acid reflux, IBS, inflammatory bowel disease and liver disease, and perform procedures such as colonoscopy and upper endoscopy to examine the digestive tract, take biopsies and remove polyps.

Where is the Cypress gastroenterology office?

The Cypress office is at 21216 Northwest Freeway, Suite 640, Cypress, TX 77429, on the Northwest Freeway (US-290). It is open Monday through Friday, 8:30 a.m. to 5:00 p.m., and closed 12:00 to 1:30 p.m. for lunch. Call (346) 340-4414.

Is the Cypress office near Towne Lake, Bridgeland and Jersey Village?

Yes. The office is at 21216 Northwest Freeway, Suite 640, Cypress, TX 77429, on the Northwest Freeway (US-290). It serves patients from Towne Lake, Bridgeland, Fairfield, Copperfield, Jersey Village and northwest Houston.

Which hospital is Dr. Khan affiliated with in Cypress?

Dr. Khan is affiliated with Memorial Hermann Cypress Hospital. If a procedure such as colonoscopy or upper endoscopy is recommended, the scheduling team confirms where it will take place and sends preparation instructions.

Do I need a referral to see a gastroenterologist?

Many insurance plans let you schedule directly with a specialist. Some plans, including many HMO plans, require a referral from your primary care physician. The office can help you check your plan’s requirements when you call to schedule.

At what age should I start colorectal cancer screening?

The U.S. Preventive Services Task Force recommends screening for adults at average risk from age 45 through 75. You may need to start earlier or be screened more often if you have a family history of colorectal cancer, a history of polyps or inflammatory bowel disease.

What is the difference between a colonoscopy and an upper endoscopy?

A colonoscopy examines the colon and rectum and is used for colorectal cancer screening and to evaluate bleeding or bowel changes. An upper endoscopy (EGD) examines the esophagus, stomach and duodenum and is used to evaluate reflux, swallowing problems, ulcers and upper abdominal pain.

Do you accept my insurance?

United Gastroenterology Associates accepts most major insurance plans, and self-pay options are available. Coverage depends on your specific plan, so the office verifies your benefits before your appointment.

Is Dr. Khan accepting new patients, and how do I book?

Yes. Dr. Muhammad Ali Khan is accepting new patients at the Cypress office (21216 Northwest Freeway, Suite 640). Call (346) 340-4414 or request an appointment online and choose Cypress.

Also Serving the Katy Community

Patients in Katy, Fulshear and Cinco Ranch can see Dr. Khan at our Katy Gastroenterology Clinic, 23920 Katy Freeway, Suite 555.

Katy Directions

NEW PATIENTS WELCOME

Book a Gastroenterology Visit in Cypress

Schedule a consultation with Dr. Khan at 21216 Northwest Freeway, Suite 640, Cypress, TX 77429. The office is accepting new patients from Cypress, Towne Lake, Bridgeland, Fairfield, Copperfield, Jersey Village and northwest Houston. Call (346) 340-4414 or request an appointment online.

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